User blog comment:Kogath/Monster Hunter 4 Ultimate for the Nintendo 3DS/@comment-24995830-20150413174534/@comment-4009941-20150416205616

I agree with Cottonmouth255, Every MH game had more realistic base than supernatural. Even the monsters that have supernatural themes and powers have realistic explanations or features. We can't explain how Kusha changes the weather but we can tell you how he has a metal skin for example and his power is limited. Even Fatalis, MH's Demon monster has realistic features and can die just like any other creature by ruining his internal organs. Or making him bleed.

We do have 2 headed creatures in RL but they are mutations and commonly die for the same reasons Cottonmouth255 said.