User blog comment:Kogath/Monster Hunter Generations Discussion/@comment-28908045-20160724213058/@comment-28908045-20160725221032

It says: Not all monsters were hunted, they have survived.

So, based on that, we can suppose that it'll be the last MH game (MH Stories doesn't count, it does not have the traditionnal graphics and hunting styles). If ever they're were to be another MH game, I think it would be in the past.