User blog comment:Kogath/Monster Hunter 4 Ultimate for the Nintendo 3DS/@comment-8874090-20150505154443/@comment-4969421-20150515130228

I'm not 100% sure but I do believe the one that only works once is the Felyne Skill equivalent for Guts (Moxie). I remember using the Daimyo Z set on my first Chaos Gore caravan quest and Guts activated twice. Still, it is an useful skill for gunners.