User blog comment:Kogath/Monster Hunter XX Discussion/@comment-6050823-20170201124240/@comment-20010297-20170202154159

But of course, it really depends on what those two elements are, and what monster you're fighting. Example, Zinogre's weakest to ice, and partially to water, so fully upgraded Zamtrios DB would be great against it, but not as great against Duram, who's weak to ice, but resistant to water.

Also, DB with both an element and status are usually pretty good.